A Longevity Brands Company · From the Founder of Retro Fitness & Serotonin Centers

The location comes with the franchise.

Serotonin Active is a standalone medical longevity franchise, built to operate inside the places where affluent, health-driven people already spend their time: fitness centers, luxury hotels, resorts, and golf clubs. We build the venue relationships at the brand level. You build the business inside them.

Confidential · No obligation · Development team responds within one business day

200–500
Square feet per suite
0
Clinical revenue lines
0
Locations built by our founder at Retro Fitness
0
Years operating medical longevity centers
01 · The Model

Franchising rebuilt around its hardest problem.

Ask any franchisor where deals die: site selection. Months of scouting, lease negotiation, and buildout risk before a dollar of revenue. Serotonin Active inverts the sequence, the way category giants once grew by opening inside big-box retail. Venue relationships are developed at the brand level so franchisees can step into pre-qualified spaces inside proven, high-traffic wellness destinations.

01

Brand-level venue partnerships

We cultivate relationships with fitness operators, hospitality groups, and club owners, then match franchisees to venues. The model is engineered so the space conversation starts long before your franchise agreement is signed.

02

A micro-footprint by design

200 to 500 square feet inside an existing destination. No standalone retail lease, no ground-up construction, no praying the market shows up. The venue already proved the traffic.

03

Recurring medical revenue

Hormone optimization and GLP-1 programs are month-over-month clinical relationships measured in years. IV therapy, peptides, and recovery modalities layer frequency on top of the base.

04

A founder who built both sides

Retro Fitness taught us how venues think. Serotonin Centers taught us how medical wellness operates at franchise scale. Serotonin Active is the convergence, built as its own system under Longevity Brands.

02 · Inside the Suite

Six clinical lines. One compact footprint.

Delivered by licensed medical providers within our compliance framework. You run the business; the clinical model governs the medicine.

Hormone Optimization

Clinically supervised HRT programs for men and women. The anchor relationship: long duration, high retention.

Recurring · Core

Medical Weight Loss

GLP-1 and GIP protocols with medical oversight, built to protect lean mass while clients train.

Recurring · Core

Peptide Therapy

FDA-compliant peptide programs serving performance, recovery, and healthspan goals.

Recurring

IV Therapy & IM Shots

Recovery infusions and energy shots, steps from the training floor, the spa, or the back nine.

High frequency

Red Light Therapy

LightStim bed sessions where suite space allows. Low labor, membership-friendly economics.

Space permitting

Hyperbaric Oxygen

HBOT recovery sessions where space allows. Premium positioning for premium venues.

Space permitting
03 · The Placement Play

The playbook that built empires inside other people's walls.

When quick-serve brands moved inside big-box retailers, they didn't just save on rent. They sold franchises faster, because the location question was answered before the candidate ever asked it. A pre-arranged venue turns "where would my unit go?" from a six-month anxiety into a one-sentence answer.

Serotonin Active applies that playbook to longevity medicine. Our leadership's two decades inside the fitness industry is the unfair advantage: the venue conversations happen founder-to-founder, operator-to-operator.

Host venue · 30,000 sq ft Serotonin Active suite 200–500 SQ FT EXISTING FOOT TRAFFIC
The venue supplies the audience. The suite supplies the outcomes.
04 · The Economics of Small

Everything a standalone clinic does, minus its heaviest costs.

Standalone wellness clinicSerotonin Active suite
Footprint2,500–5,000+ sq ft200–500 sq ft
Site selectionMonths of scouting and lease riskVenue partnerships built at the brand level
BuildoutGround-up retail constructionSuite conversion inside an existing space
First customersAcquired from zero, ad dollar by ad dollarThe venue's existing members and guests
Brand trustEarned aloneSerotonin pedigree + the venue's own halo
"Most venues offer an experience. The winners of the next decade will offer outcomes. Serotonin Active is how a great venue starts delivering medical-grade results, without becoming a medical company."
Eric Casaburi · Founder, Retro Fitness · Serotonin Centers · Serotonin Active
05 · Path to Ownership

Five steps. No mystery.

Inquire

Submit the request. A development lead responds within one business day.

Intro Call

Your market, your background, your capital position, your venue relationships.

FDD Review

The full disclosure document and complete economics, with time for your advisors.

Discovery Day

Meet leadership. Tour an operating Serotonin location. Pressure-test everything.

Launch

Venue placement, suite conversion, training, and opening support.

06 · Common Questions

Direct answers, up front.

What is a Serotonin Active franchise?
A standalone medical longevity franchise operating a 200 to 500 square foot suite inside a high-traffic wellness venue: a fitness center, luxury hotel, resort, or golf club. Franchisees deliver hormone optimization, GLP-1 medical weight loss, peptides, and IV recovery therapy to the venue's members, guests, and surrounding market.
Do I have to find my own location?
Site selection is led at the brand level. Our venue partnership model is designed to match franchisees with pre-qualified spaces inside proven venues, so your launch timeline is measured in months of buildout, not years of real estate scouting. Venue placement is a defined, supported step in the development process.
How much does it cost?
The estimated total initial investment is approximately $350,000 to $500,000, including a $39,000 initial franchise fee (preliminary estimates; final figures in the Franchise Disclosure Document). The micro-footprint model is built to require substantially less capital than a standalone clinic.
Is this the same company as Serotonin Centers?
No. Serotonin Active USA is a separate franchise system owned by Longevity Brands LLC, with its own Franchise Disclosure Document. Both brands were founded by Eric Casaburi and share the Serotonin standard of care.
Founding Markets Open

Territories are exclusive. The best venues in your market can host exactly one of these.

Tell us about your market and your background. If there's a fit, you'll know within one call.

Request Franchise Info